Endocrine Abstracts

The therapy of hyperprolactinemia with dopamine agonists (DAs) is highly effective in the majority of cases (1). However, some patients fail to achieve normal prolactin levels and develop drug resistance towards prescribed medicine. This case study describes a medical history of The Georgian National Institute of Endocrinology patient, with a drug-resistant hyperprolactinemia and inability to conceive. The patient’s MRI scan result has not indicated incidence of pr...

Even in the presence of normally circulating androgens, the imbalance between estrogen and androgen in males between the prepubertal and pubertal periods may have an impact on male reproductive function. While there are many variables that affect how each person reaches puberty at different times, boys who are becoming more obese have higher aromatase activity. This enzyme turns testosterone into estradiol permanently, which lowers testosterone levels and raises estrogen level...